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Southern Nana’s Meatloaf Recipe

Southern Nana’s Meatloaf is a comforting, classic dish that’s perfect for family dinners. Made with a combination of ground beef, spices, and a savory glaze, this meatloaf is moist, flavorful, and incredibly easy to prepare. Passed down through generations, this recipe is full of love and tradition, making it a true family favorite.

Table of Contents

Ingredients

For the Meatloaf

  • 2 lbs ground beef (80/20 blend)
  • 1 cup breadcrumbs
  • 1 medium onion, finely chopped
  • 2 cloves garlic, minced
  • 1/4 cup milk
  • 2 large eggs
  • 1 tablespoon Worcestershire sauce
  • 1 teaspoon salt
  • 1/2 teaspoon black pepper
  • 1/2 teaspoon dried thyme
  • 1/2 teaspoon dried oregano
  • 1/2 teaspoon smoked paprika

For the Glaze

  • 1/2 cup ketchup
  • 2 tablespoons brown sugar
  • 1 tablespoon Dijon mustard
  • 1 tablespoon apple cider vinegar

Instructions

Step 1: Preheat the Oven

  1. Preheat your oven to 350°F (175°C). Line a baking sheet with parchment paper or lightly grease a loaf pan.

Step 2: Mix the Meatloaf Ingredients

  1. In a large mixing bowl, combine the ground beef, breadcrumbs, chopped onion, minced garlic, milk, eggs, Worcestershire sauce, salt, black pepper, dried thyme, dried oregano, and smoked paprika.
  2. Mix until all ingredients are well combined, being careful not to overmix to keep the meatloaf tender.

Step 3: Shape the Meatloaf

  1. Transfer the meat mixture to the prepared baking sheet or loaf pan and shape it into a loaf.

Step 4: Prepare the Glaze

  1. In a small bowl, whisk together the ketchup, brown sugar, Dijon mustard, and apple cider vinegar until smooth.

Step 5: Glaze and Bake

  1. Spread half of the glaze evenly over the top of the meatloaf.
  2. Bake in the preheated oven for 1 hour. Remove the meatloaf from the oven, spread the remaining glaze over the top, and return it to the oven.
  3. Continue baking for an additional 15-20 minutes, or until the internal temperature reaches 160°F (71°C).

Step 6: Rest and Serve

  1. Allow the meatloaf to rest for 10 minutes before slicing. This helps the juices redistribute and keeps the meatloaf moist.
  2. Slice and serve warm.

Cooking Tips & Notes

  • Ground Beef: An 80/20 blend of ground beef works best for a juicy and flavorful meatloaf. Using leaner beef may result in a drier texture.
  • Breadcrumbs: Use plain or seasoned breadcrumbs, or substitute with crushed saltine crackers or oats for a different texture.
  • Do Not Overmix: Mixing the ingredients just until combined helps keep the meatloaf tender.

Variations

  • BBQ Meatloaf: Substitute the ketchup in the glaze with your favorite barbecue sauce for a smoky flavor.
  • Cheese-Stuffed Meatloaf: Add 1 cup of shredded cheddar or mozzarella cheese to the center of the meatloaf for a cheesy surprise.
  • Vegetable Additions: Mix in finely chopped bell peppers, carrots, or celery for added texture and nutrition.
  • Turkey Meatloaf: Use ground turkey instead of beef for a lighter version of this classic dish.

Frequently Asked Questions (FAQs)

1. Can I Make This Meatloaf Ahead of Time?

Yes, you can prepare the meatloaf mixture and shape it ahead of time. Cover and refrigerate for up to 1 day before baking. Add the glaze just before baking.

2. How Do I Store Leftover Meatloaf?

Store leftover meatloaf in an airtight container in the refrigerator for up to 4 days. Reheat in the oven or microwave until warmed through.

3. Can I Freeze Meatloaf?

Yes, you can freeze meatloaf. Wrap it tightly in plastic wrap and foil, then freeze for up to 3 months. Thaw in the refrigerator before reheating.

4. What Can I Use Instead of Breadcrumbs?

You can use crushed saltine crackers, oats, or even panko breadcrumbs as a substitute for regular breadcrumbs.

Serving Suggestions

  • Mashed Potatoes: Serve with creamy mashed potatoes for a classic pairing.
  • Roasted Vegetables: Pair with roasted carrots, green beans, or Brussels sprouts for a balanced meal.
  • Gravy: Drizzle with brown gravy for extra richness and flavor.
  • Sandwiches: Use leftover meatloaf slices to make delicious sandwiches with toasted bread and your favorite condiments.

Southern Nana’s Meatloaf is a comforting and delicious dish that’s full of flavor and perfect for family dinners. With its savory blend of spices, tender texture, and a sweet and tangy glaze, this meatloaf is sure to become a family favorite. Whether served with mashed potatoes or as part of a hearty sandwich, this classic recipe brings warmth and tradition to the dinner table. Give it a try and enjoy the timeless taste of Southern comfort!

 

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